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Last year, about 1 in 26 children had food allergies. The Associated Press quotes experts who note that the increase might be due to parents being more aware and quicker to have their children checked for these allergies. A doubling in peanut allergies and children taking longer to outgrow milk and egg allergies than in the past also contributed, according to other experts quoted by the AP. The findings were based on a survey of households of 9,500 U.S. children under age 18. Children with food allergies were more likely to have asthma, eczema and respiratory problems than kids without food allergies, according to a CDC study. The study also found that the number of children hospitalized for food allergies has increased.
Pneumonia Vaccine Recommended for Smokers
Federal health officials are recommending that all smokers under 65 years old receive the pneumococcal vaccine to protect against the bacteria that cause pneumonia and meningitis, among other illnesses. The Advisory Committee on Immunization Practices made the recommendation this week, based on studies showing that smokers are four times more likely than nonsmokers to suffer pneumococcal disease, and the risk rises with the number of cigarettes smoked each day

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Glucocorticoids Not as Effective in Obese Patients With Asthma
NEW YORK -- October 24, 2008 -- Glucocorticoids are 40% less effective in overweight and obese patients with asthma than in those of normal weight, according to a study in the October issue of American Journal of Respiratory and Critical Care Medicine.
The study also identified a potential mechanism involved in the resistance, which suggests therapeutic targets for future medications.
This study identifies what could be a significant issue for the 20 million Americans with asthma, said E. Rand Sutherland, MD, National Jewish Health, Denver, Colorado.
These findings should spur doctors to carefully evaluate response to treatment in overweight and obese asthmatics and consider optimising therapeutic regimens as indicated. We also hope they will spur additional research into the treatment of obese patients with asthma.
Dr. Sutherland and colleagues enrolled 45 nonsmoking adults, 33 of whom had asthma, and measured the response of cells in the blood and the lungs to dexamethasone.
When the researchers applied dexamethasone to cultures of the participants' blood cells, they found that the steroids did not increase MAP kinase phosphatase-1 (MKP-1) as effectively in overweight and obese asthmatics when compared to lean asthmatics.
Dexamethasone increased the levels of MKP-1 by 5.27 times in cultured blood cells from lean asthma patients, whereas MKP-1 levels in overweight and obese asthmatics increased by only 3.11 times, a 41% smaller response. The heavier a person was the less their cells were likely to respond to dexamethasone

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