Allergy asthma immunology
PHILADELPHIA (CBS 3) Millions of people with asthma and allergies have turned to the popular prescription drug, Singulair to help them breathe easier. But some patients say they're suffering horrible side effects from a drug that was supposed to make them feel better. Some parents even believe Singulair can lead to suicide.6-year-old Matthew Cook is a happy first grader who loves soccer and 14-year-old Matt Farrone is a freshman in high school, already looking toward college. They've never met but share a horrifying experience.'I just didn't want to be alive anymore, I wished I wasn't born,' Farrone said.'He just threw himself on the floor and said, 'I want to die, I just want to die',' Cook's mom said.Their parents say, seemingly out of nowhere, both boys became severely anxious and depressed.'He was afraid to leave the house, afraid to go to school, afraid to leave me,' Farrone's mom said.Matthew Cook threatened to kill his brother and sister. 'It just tore us apart,' Cook's mom said.Matt and Matthew had something else in common. They both took Singulair for asthma
The protein glows under blue and ultraviolet light, allowing researchers to illuminate tumor cells, trace toxins and to monitor genes as they turn on and off.
'The discovery is of great use for humanity. In the past 10 years, in almost every second publication in the big journals, people are using this method,' Lars Thelander, a member of the Nobel Committee for Chemistry, said in an interview.
'We can simply look inside an animal and say where has this gene been turned on, when is it turned on and when the protein is made, where does it go?' Chalfie, 61, said in a telephone interview.
'They have their own flashlight telling you where they are.' Tsien, 56, a Howard Hughes Medical Institute investigator, used coral proteins too, and extended the palette beyond green to yellow, blue and other colors, allowing scientists to follow several different biological processes at the same time. He said asthma kept him indoors as a child, so he spent hours playing with colors as part of chemistry experiments in his basement. Chalfie said he missed the first call from the Nobel committee: 'I looked on the computer, my laptop, and I found that I had won the prize. I slept through the phone call.'
GFP has been used for art as well as for science. A green-glowing bunny named Alba was made in 2000 at the request of Chicago artist Eduardo Kac and green-glowing pigs have been gene engineered and bred to make green-glowing piglets. No one is sure what the jellyfish use the glow for
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